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Alexion Pharmaceuticals Portfolio Analytics Head in Boston, Massachusetts

Some opportunities happen only once in a lifetime - like a job where you have the chance to change lives. At Alexion, people living with rare and devastating diseases are our Guiding Star. We are driven to continuously innovate and create meaningful value in all we do to help patients and families fully live their best lives. We value the uniqueness and diversity of our employees and recognize that nurturing the diverse perspectives and strengths of our people translates into innovative breakthroughs for patients.

This is what you will do:

At Alexion, AstraZeneca Rare Disease, we are innovators, leaders, and collaborators. At the heart of everything we do is an intense desire to pursue the toughest challenges and truly change the world for people living with rare and devastating diseases.

The VISion team (Value, Insights Strategy at Alexion) is a fully integrated commercial strategy team, aligning global marketing, new product planning, and commercial excellence across all therapeutic and disease areas. The purpose of VISion is to partner with both global colleagues (R&D, Operations, Corporate Affairs, Finance, et al) and regional and local Commercial colleagues to ensure the successful development and launch of innovative therapies that will deliver value for all our stakeholders. Our unique culture is centered on collaboration, authenticity, creativity and pushing the boundaries on everything we do to advance patient care.

The Portfolio Analytics Head both leads a team of three and conducts their own robust portfolio forecasting and reporting capabilities to define financial opportunities for the pipeline which aid in enterprise-wide portfolio decision making. This leadership position will also personally support assessment of internal and external opportunities, including rationale, technical and commercial considerations, in partnership with key organization stakeholders. As the leader of the team, the ideal candidate is highly collaborative and confident interfacing with senior management (Global Program Leaders, Regional Commercial Leaders, and Therapeutic Area Leaders) on internal governance interactions, and executive leadership on key investment decisions.

The key focus of this role is lead the development and delivery of financial and analytical support, producing long-term topline and patient forecasting to enable data-driven decision making (integrated with market insights), demand and infrastructure planning, and deeper comprehension of underlying commercial opportunities. Outputs of this work will include the development of strategic business cases and scenarios and inputs into portfolio prioritization. As leader of the Portfolio Analytics team, this role will also set and maintain the standards, assumptions, and processes for this work.

You will be responsible for:

  • Set and maintain the standards, assumptions, processes and other important criteria for portfolio insights and analytics.

  • Lead the team that runs annual processes related to portfolio assessment, long-term planning, management, and prioritization for Alexion portfolio, including analyzing changes with respect to prior evaluations.

  • Guide and facilitate cross-functional discussions at program and portfolio level to: influence program level strategic and forecasting discussions; provide portfolio view and cross-product knowledge; and generate alignment on company long-term strategic plans.

  • Develop and coach colleagues to use models for scenario planning with a variety of decision frameworks, draw insight from these models, and present and explain them to stakeholders.

  • Partner across Commercial Excellence, Finance, Epidemiology, HEOR, DGB, and other functions to align on data sources and vendors, as compliant and appropriate.

  • Ensure we maintain the utmost integrity and respect for data privacy and all key rules and regulations.

  • Set the tone for collaborative insight generation and analyses; bring the outside in; encourage colleagues to actively seek out and listen to a diverse set of stakeholders to better inform analyses.

  • Partner across Commercial Excellence to ensure integration of insights from all sources into the development and presentation of analyses.

  • Maintain a close, collaborative partnership with Finance, determine how to best collaborate on and exchange information to support consolidation, analysis, and management reporting of long- and mid-term planning.

  • Partner with New Product Strategy and key stakeholders to lead assessments for potential business cases for research assets; support assessments for business development opportunities as needed.

  • Lead partnership with Global Operations on integrated business planning (demand planning with scenario planning).

  • Ensure data integrity and provide ad-hoc and standard reports and presentations to Executive Team; identify variations from prior strategic plans and operational planning; provide information around potential consequences and recommendations for corrective actions.

  • Maintain relevant knowledge of external market landscape, pipeline and competition in core therapeutic areas and support development of internal expertise in potential new areas.

  • Drive optimization and continuous improvement of strategic portfolio and financial planning processes, systems, and operational excellence in partnership with the CFO team.

  • Ability to flex and fill needs over time, such as modeling new, innovative opportunities for which there is no precedent.

    You will need to have:

  • Bachelor Degree in Business/Finance, MBA preferred; is a strong plus

  • At least 12 years of experience, preferably in the biopharma/biotech industry, in one or more of the following areas: strategic planning, corporate development/business development, business analytics, market research, finance/controlling, or strategy/management consulting.

  • Previous experience in leading global processes spanning long term business planning, portfolio analytics and portfolio prioritization supporting Pharmaceutical R&D pipeline and Business Unit/Regional Unit P&L analysis, including detailed sales forecasting, cost analysis and project economic evaluation.

  • Strong global acumen and understanding of international markets.

  • Impressive leadership and coaching skills, with prior demonstration of ability to lead diverse, multidisciplinary teams to achieve challenging objectives.

  • Exceptional quantitative and analytical modeling skills with an ability to translate complex business questions into financial models.

  • The ability to manipulate heavy sets of data, including building and updating discounted cash flow and technical probability assessment.

  • Mastery of Excel and modeling software.

  • Ability to think strategically about current portfolio and future evolution in the context of competition and external trends.

  • Strong written and verbal communication suitable for senior executive audience.

  • Highly collaborative, strong interpersonal skills and cross-functional team experience; ability to lead and influence within a matrix.

  • Willingness to travel (domestic, international) 10% of the time, in accordance with company policies

  • The duties of this role are generally conducted in an office environment. As is typical of an office-based role, employees must be able, with or without an accommodation to: use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours.

    We would prefer for you to have:

  • Experience analyzing and developing economic proposals for external innovation, including licensing and acquisition opportunities.

  • Scientific background is a plus.

  • Direct experience performing a similar role in-house or in consulting

  • Ex-U.S. experience.


Alexion is a global biopharmaceutical company focused on serving patients and families affected by rare diseases and devastating conditions through the discovery, development and commercialization of life-changing medicines. Headquartered in Boston, Massachusetts, Alexion has offices around the globe and serves patients in more than 50 countries. Further information about Alexion can be found at: www.alexion.com.

Alexion is proud to be an Equal Employment Opportunity and Affirmative Action employer. We are committed to fostering a culture of belonging where every single person can belong because of their uniqueness. The Company will not make decisions about employment, training, compensation, promotion, and other terms and conditions of employment based on race, color, religion, creed or lack thereof, sex, sexual orientation, age, ancestry, national origin, ethnicity, citizenship status, marital status, parental status (including adoption or surrogacy), pregnancy (including childbirth, breastfeeding, or related medical conditions), military status, protected veteran status, disability, medical condition, gender identity or expression, genetic information, mental illness or other characteristics protected by law. Alexion provides reasonable accommodations to meet the needs of candidates and employees. To begin an interactive dialogue with Alexion regarding an accommodation, please contact accommodations@Alexion.com. Alexion participates in E-Verify.

As a leading employer in our industry, Alexion offers a highly competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, 401(k) with company match, tuition reimbursement, relocation assistance and much more.

AstraZeneca completed its acquisition of Alexion, marking the creation of Alexion, AstraZeneca Rare Disease. If you're interested in career opportunities with AstraZeneca, click here (https://careers.astrazeneca.com/) .