Pfizer Global Director in New York City, New York
To support the strategic goals of the Oncology Business by developing best in class evidence, HTA tools and strategy in support of patient access for sasanlimab.
Bladder cancer is among the most common cancer types worldwide, with approximately 400,000 new cases diagnosed annually. Non-muscle invasive bladder cancer (NMIBC) represents approximately 75% of new bladder cancer cases. While NMIBC is not immediately life-threatening, recurrence and progression are common with some estimates indicating that 31-78% of patients may experience recurrence within five years of diagnosis, and approximately 10-20% will progress to muscle-invasive disease. Sasanlimab is a new anti-programmed cell death protein-1 (PD-1) inhibitor with sub-cutaneous administration. The ongoing Phase 3 Study CREST is designed to demonstrate the degree to which sasanlimab addresses the unmet need in patients with high-risk, BCG-naïve NMIBC.
This role directly impacts the ability to achieve business objectives on a global basis by providing strategic guidance and robust evidence development relevant to achieve optimal global patient access by demonstrating the value of our breast cancer medicines. The HEOR Director will be responsible for developing best in class launch deliverables to key external stakeholders. This role will be predominantly focused on supporting the Global business.
This position will function with a 'One Patient & Health Impact' mindset and will work in a closely aligned fashion with the RLIOPHI team members to ensure there is a single and coordinated view on strategy and delivery from the RLIO PHI team to the oncology business. This position reports to the RLIO Integrated Team Lead
Lead the development of Health Economics & Outcomes Research (HEOR) strategy to support the value of sasanlimab in the Oncology Business Unit (BU) in close partnership with the cross-functional matrix team.
Lead the design and execution of Global HEOR studies and projects (including Non-Interventional Studies, registries, burden of illness studies, epidemiology studies etc.).
Incorporate humanistic and economic endpoints into clinical trials across all phases of product development to build comprehensive trial-based evidence in line with overall medical strategy for the assets and to ensure global reimbursement and access requirements. Provide strategic input in the selection of relevant patient population and comparators within clinical trials to enable successful negotiations, reimbursement, and appropriate patient access with global payer and regulatory decision makers.
Development and validation of new Patient Reported Outcomes measures as appropriate for inclusion across clinical trials, registries, and prospective real world studies.
Identify opportunities to partner with Oncology BU external customers to conduct HEOR projects in support of asset strategies
Lead the timely development of launch and post launch deliverables including global value dossiers (GVD and AMCP), evidence blueprints, economic models, and innovative tools to successfully support Global and US launch and post-launch reimbursement and access requirements in conjunction with the regions/countries.
Lead the coordination of input from local country/regional teams on evidence needs and ensure that the input is appropriately incorporated to develop and integrate the evidence strategy to support global market access needs at launch and through lifecycle.
Develop strategic partnerships and research collaborations with key external experts, healthcare policy makers, payers, and various academic and community oncology settings to support asset strategies.
Provide strategic guidance and content guidance in reimbursement (re)negotiations for Pfizer products.
Lead the development of appropriate data dissemination plans and communicate evidence generated via publications and conference presentations.
Partner with internal stakeholders to ensure appropriate customer facing dissemination of HEOR materials per FDA guidance and internal SOPs
Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
Clinical degree (e.g. PharmD, MD) or Masters degree (MSc, MPH) in health services research, public health, epidemiology, or health economics with a preferred Doctoral degree (PhD, DrPH, ScD) in health services research, public health, epidemiology, or health economics.
Minimum 8 years' experience in health outcomes and related fields, 5 of which are as part of global health economics and/or outcomes research teams in a pharmaceutical company.
Strong working knowledge of the technical and methodological aspects of registries and observational study design, implementation, analysis and interpretation. Capable of independently managing complex registry and non-interventional study projects.
In depth understanding of Pharmacoeconomics and Health-related Quality of Life
Knowledge and experience in the oncology therapeutic area is preferred
Strong understanding of the US healthcare market is desirable
Experience with HTA organizations such as NICE, SMC, PBAC is desirable
Excellent interpersonal skills required: ability to understand and respond to multiple internal and external customers
Excellent oral and written English communication skills required
Strong project management abilities (contracting, budgeting, vendor management) essential. Demonstrated ability to manage multiple projects (multitask) involving complex processes, significant budget, competing deadlines and rapidly shifting priorities
Ability to influence key members of medical and commercial teams constructively and without conflict
Skilled in functioning within a matrix organization where managing through influence is required
Organized and detail oriented with the ability to anticipate needs and to work proactively to prioritize & address/resolve
Change oriented, comfortable responding to unexpected demands with tight timelines; team player
Other Job Details:
Last Date to Apply for Job: November 5th, 2021
Additional Location Information: New York, NY; Collegeville, PA; US - Remote; Europe - Remote; Europe - Any Pfizer site; Canada - Remote; Latin America - Remote
Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment. As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.
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EEO & Employment Eligibility
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