Pfizer Senior Associate Scientist, Viral Vaccines in Pearl River, New York
The incumbent is responsible for supporting the preclinical evaluation and early clinical development of candidate viral vaccines. The incumbent will perform various assays to monitor the immune responses elicited by vaccine candidates. This position will also be responsible for maintaining cell lines, weekly processing of red blood cells, and preparing samples for testing. The incumbent will assist with molecular and virology work to generate plasmid constructs for RNA and reverse genetic virus stocks plus optimizing RNA vaccines. Work is to be done in a compliant manner according to relevant SOP guidelines and cGLP and/or cGMP guidelines where appropriate. The incumbent will be part of a dynamic team and should possess a strong work ethic and collaborative spirit.
Analyze immune responses to vaccine candidates using techniques that include (but are not limited to) cell culture, hemagglutination inhibition assays, neutralization assays, ELISAs, ELISPOT and RT-PCR. Perform molecular techniques that include (but are not limited to) PCR, cloning, and sequence and virology techniques that include virus propagation in cell culture. Independently interpret and summarize experimental data. Present experimental results at group meetings. Generate and characterize reagents used to perform necessary assays and support maintenance of laboratory supplies. Maintain laboratory notebooks in compliance with the Pfizer Laboratory Notebook Policy. Performs other duties as assigned. Satisfactorily complete all safety training in conformance with Departmental requirements. Where applicable, performs job responsibilities in compliance with cGMP/GLP and all other regulatory agency requirements.
Master's degree in Virology, Immunology or Molecular Biology with 2 years of research experience OR B.S. with 6 years of laboratory research experience required; industry experience preferred.
Knowledge of methods in influenza virology and immunology highly preferred.
Proficiency with personal computers including Word, Excel or Graphpad Prism, PowerPoint and relevant scientific software is desirable.
Basic laboratory training in aseptic technique is essential. Ability to work with infectious agents safely. The capacity to work effectively in a highly visible research program with time-constrained milestones.
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